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Pamela Poblete-Gutiérrez Selected Research

Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency)

3/2022The Porphyrias.
3/2015Biallelic inactivation of protoporphyrinogen oxidase and hydroxymethylbilane synthase is associated with liver cancer in acute porphyrias.
11/2011Digenic inheritance of mutations in the coproporphyrinogen oxidase and protoporphyrinogen oxidase genes in a unique type of porphyria.
10/2010The acute hepatic porphyrias: current status and future challenges.
9/2010Hepatocellular carcinoma in variegate porphyria: a serious complication.
7/2006[Identification of mutations in the protoporphyrin oxidase gene and its diagnostic implications in porphyria variegata in Chile].

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Pamela Poblete-Gutiérrez Research Topics

Disease

6Variegate Porphyria (Protoporphyrinogen Oxidase Deficiency)
03/2022 - 07/2006
6Porphyrias (Porphyria)
03/2022 - 06/2004
5Porphyria Cutanea Tarda
03/2022 - 06/2004
2Acute Intermittent Porphyria (Porphyria, Acute)
03/2015 - 10/2010
2Hereditary Coproporphyria (Coproporphyrinogen Oxidase Deficiency)
11/2011 - 10/2010
2Psoriatic Arthritis
01/2011 - 11/2008
2Infections
10/2010 - 11/2007
2Neoplasms (Cancer)
02/2009 - 09/2006
2Exanthema (Rash)
11/2008 - 11/2008
1Metabolic Diseases (Metabolic Disease)
03/2022
1Erythropoietic Porphyria (Congenital Erythropoietic Porphyria)
03/2022
1Liver Neoplasms (Liver Cancer)
03/2015
1Reactive Arthritis (Reiter Disease)
01/2011
1Spondylarthropathies
01/2011
1Hepatic Porphyrias (Hepatic Porphyria)
10/2010
1Liver Diseases (Liver Disease)
10/2010
1Alcoholism (Alcohol Abuse)
10/2010
1Hemochromatosis (Bronze Diabetes)
10/2010
1Iron Overload
10/2010
1Hepatocellular Carcinoma (Hepatoma)
09/2010
1Carcinogenesis
02/2009
1Rheumatoid Arthritis
11/2008
1Multiple Myeloma
11/2008
1Psoriasis (Pustulosis Palmaris et Plantaris)
11/2008
1Ankylosing Spondylitis
11/2008
1Pyoderma Gangrenosum
11/2008
1Leiomyoma (Uterine Fibroids)
08/2008
1Dermatitis
11/2007
1Carcinoma (Carcinomatosis)
11/2007
1Hyperpigmentation
11/2007
1Lichen Planus (Lichen Ruber Planus)
11/2007
1Skin Diseases (Skin Disease)
09/2006
1Epidermolytic Hyperkeratosis (Bullous Congenital Ichthyosiform Erythroderma)
09/2006
1Leiomyomatosis
09/2006
1Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara)
09/2006

Drug/Important Bio-Agent (IBA)

7EnzymesIBA
03/2022 - 06/2004
6Heme (Haem)IBA
03/2022 - 06/2004
4Protoporphyrinogen Oxidase (Protox)IBA
03/2015 - 07/2006
3Uroporphyrinogen Decarboxylase (Uroporphyrinogen III Decarboxylase)IBA
10/2010 - 06/2004
2Fumarate Hydratase (Fumarase)IBA
08/2008 - 09/2006
1Hydroxymethylbilane Synthase (Porphobilinogen Deaminase)IBA
03/2015
1PorphyrinsIBA
11/2011
1Coproporphyrinogen Oxidase (Coproporphyrinogen III Oxidases)IBA
11/2011
1Rheumatoid FactorIBA
01/2011
1HLA-B27 Antigen (HLA B27 Antigen)IBA
01/2011
1HydrocarbonsIBA
10/2010
1Porphobilinogen Synthase (delta-Aminolevulinate Dehydratase)IBA
10/2010
1Acute Hepatic PorphyriaIBA
09/2010
1Cytochrome P-450 CYP1A2 (CYP1A2)IBA
08/2010
1NF-kappa B (NF-kB)IBA
02/2009
1TOR Serine-Threonine KinasesIBA
02/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2008
1Adalimumab (Humira)FDA Link
11/2008
1ColchicineFDA LinkGeneric
11/2008
1Adrenal Cortex Hormones (Corticosteroids)IBA
11/2007
1Cisplatin (Platino)FDA LinkGeneric
11/2007
1Hydroxyurea (Hydrea)FDA LinkGeneric
11/2007
1Ointments (Pastes)IBA
11/2007
1Bleomycin (Blenoxane)FDA LinkGeneric
11/2007
1Pharmaceutical PreparationsIBA
11/2007
1Etoposide (VP 16)FDA LinkGeneric
11/2007
1Keratins (Keratin)IBA
09/2006
1Complement System Proteins (Complement)IBA
09/2006
1Keratin-1IBA
09/2006
1Keratin-10IBA
09/2006
1Keratin-5 (Keratin 5)IBA
09/2006
1Oxidoreductases (Dehydrogenase)IBA
07/2006
1protoporphyrin IXIBA
07/2006

Therapy/Procedure

5Therapeutics
03/2022 - 11/2007
1Stem Cell Transplantation
11/2008